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But heat loosens the hold these protein chains have on the carotenoids and releases the astaxanthin, turning the shrimp its lovely shade of pink. This is the same reason lobsters turn red when you cook them. News U. Politics Joe Biden Congress Extremism. Special Projects Highline. HuffPost Personal Video Horoscopes. Get the Shrimp Cakes recipe by Simply Recipes. Get the Shrimp Dip recipe by Simply Recipes. Get the Cioppino recipe by Simply Recipes. Suggest a correction.

Parchment, Wax And Freezer Paper. Thanksgiving Without Turkey? Newsletter Sign Up. This is a large group of colour molecules, the molecule that turns a carrot carotene orange is also part of it.

However, in raw shrimp this astaxanhin is bound to proteins forming a complex called crustacyanin. This causes the two molecules bound together to show as blue! Light cannot be reflected in the right way for it to show the pink colour.

When shrimp are cooked the protein denatures it unfolds and changes shape due to the high temperatures. As a result, the astaxanthin is unbound now and now reflects the light differently, causing the shrimp to be pink! It probably is a combination of time and temperature that will determine whether enough of the protein has denatured for the shrimp to turn pink.

This depends on the exact composition of the shrimp. Also, not all proteins will break down at the exact same time. You seem to be able to watch into the shrimp slightly. During cooking this translucency changes in a white colour, as it does for many other white fish. This change of colour is similar to that of an egg white turning white when boiled or cooked and is caused by the same mechanism: protein denaturation. Proteins are heat sensitive. Proteins tend to be folded up in all sorts of complex configurations helices, curls.

But when they are heated to high enough temperatures they can uncurl and extend. It is not just heat that can cause this transformation from translucent to white. Acids can do the same by denaturing the proteins.

It is a similar process going on but caused by acidity instead of heat. When you cook shrimp it is not just the colour that changes, the shape changes as well. Once the shrimps starts heating up considerably, they will start to curl up.






















It can be helpful to get your prescription from the same pharmacist each time as some pharmacists keep records of the medication they dispense and can help with questions about prescriptions.

There are also lots of other ways in which your pharmacist can help you. Anti-epileptic drugs AEDs are the main type of treatment for most people with epilepsy that aims to stop seizures from happening. In August , the Government asked pharmaceutical companies to ensure they have a minimum six week stockpile of prescription-only and pharmacy-only medicines in case of potential delays at UK borders after Brexit on 29 March Information and training for people who are responsible for giving emergency medication to people with epilepsy.

If you have difficulties with taking your medication the following strategies and tools might be helpful. If you have just been diagnosed with epilepsy, you may have questions about medication and treatment. You might want to talk to your specialist, epilepsy specialist nurse or GP, about your epilepsy. You might also want to talk to your pharmacist about your treatment.

Our confidential epilepsy helpline provides information and emotional support. You can also get in contact with us through Facebook and Twitter. The decision whether to start taking anti-epileptic drugs AEDs can be difficult, and there is a lot to think about. Here we look at the benefits and risks of taking, or not taking, AEDs. Managing your treatment is an important part of managing your epilepsy, and seeing whether your medication is working.

This might include having a care plan, including a treatment plan. If someone has not had a seizure for two or more years then they may think about withdrawing coming off their AEDs. How doctors monitor epilepsy including therapeutic drug monitoring which checks the effectiveness of drugs taken by people with epilepsy. AEDs are available in a number of different forms, including tablets, capsules, liquids and syrups.

You usually need to take the medicine every day. Your specialist will start you on a low dose and gradually increase it until your seizures stop. If the first medicine you try does not work, your doctor may recommend trying another type. It's important you follow any advice about when to take AEDs and how much to take. Never suddenly stop taking an AED — doing so could cause a seizure. If you have not had a seizure for a few years, ask your doctor if you might be able to stop treatment. If they think it's safe, your dose will be reduced gradually over time.

While taking AEDs, do not take any other medicines, including over-the-counter medicines or complementary medicines, without speaking to your GP or specialist. Other medicines could affect how well your AED works. Side effects are common when starting treatment with AEDs. Some may appear soon after starting treatment and pass in a few days or weeks, while others may not appear for a few weeks. Contact your GP or specialist if you have symptoms similar to being drunk, such as unsteadiness, poor concentration and being sick.

This could mean your dose is too high. For information about the side effects of your medicine, check the information leaflet that comes with it. In these cases, there's a good chance that your seizures could stop completely after surgery. If your epilepsy is poorly controlled after trying several AEDs, you may be referred to a specialist epilepsy centre to see if surgery might be possible. The results of these tests will help you and your specialist decide if surgery is an option for you, and what the result of surgery might be.

Surgery for epilepsy is usually carried out under general anaesthetic , where you're asleep. The surgeon makes a small cut in your scalp and creates an opening in your skull so they can remove the affected part of the brain. Your seizures may not stop straight away, so you might need to keep taking AEDs for 1 to 2 years. There's a risk of complications from surgery, such as problems with your memory, mood or vision.

These problems may improve over time, or they may be permanent. If AEDs are not controlling your seizures and brain surgery is not suitable for you, there are other procedures that could help. Vagus nerve stimulation VNS is where a small electrical device similar to a pacemaker is placed under the skin of your chest.

The device is attached to a wire that goes under your skin and connects to a nerve in your neck called the vagus nerve. Bursts of electricity are sent along the wire to the nerve. It's thought this can help control seizures by changing the electrical signals in the brain. Individuals may find that complementary therapies boost the effectiveness of their seizure medications. People must check with their doctor before beginning any of these therapies.

Herbal remedies , including kava , valerian , passionflower , and chamomile , may have relaxing and calming effects and a positive impact on seizures. In contrast, stimulating herbs, such as ginseng and gingko , may worsen seizures. Nutrients such as vitamin B6 , magnesium , vitamin E , and omega-3 fatty acids may reduce seizure frequency.

Research also shows that thiamine may help brain function in people with epilepsy. A healthcare professional shows a person that activity in real time. This can allow the person to understand their own body better. Biofeedback has been successful in teaching people to recognize warning signs and act to prevent a full-blown seizure. The role of acupuncture in treating epilepsy is unclear. Some research has found it ineffective in treating seizures and improving quality of life.

In comparison, other scientists present it as a promising therapy. A growing number of people with epilepsy report that using cannabis is beneficial to their condition and, in some cases, results in nearly complete seizure control.

The Food and Drug Administration FDA recently approved the cannabis-based drug Epidiolex to treat some rare and severe types of epilepsy. A range of factors, including trauma, infections, and genetics, can cause epilepsy and seizures. Sometimes, there is no identifiable cause.

Usually, anti-epileptic drugs treat seizures and epilepsy successfully. However, side effects can occur with these medications. Alternative therapies also exist, including brain surgery, implanted devices, special diets, biofeedback, and medical cannabis.

Epilepsy is a fairly common neurological condition characterized by recurrent seizures. In this article, learn about the different types of epilepsy…. Epilepsy is a condition that causes seizures. It is relatively common in children. Learn about its causes, symptoms, and treatments here. Absence seizures cause brief lapses in consciousness that may look similar to daydreaming. This article looks at their causes, symptoms, and…. An abnormal electrical discharge in the brain causes a seizure.






















These were what concerned Mao, for example massive inequality, rampant corruption an the dimunition of the common good against individual selfishness and greed. Was Mao Tse Tung a good leader? David P. Mar 19, This is a short but at the same time huge question. Explanation: Mao was one of the most influential figures in 20th century history and it can be argued that he was both a good and bad leader.

How did Mao Tse Tung come to power? What reforms did Mao Tse Tung make? Why were the states which surrounded the USSR known as "satellite" states? Question 6d Despite all this, Jeff Wasserstrom, a professor of Chinese history at the University of California, Irvine, said Mao remained a revered figure in some parts of China.

Zhang, who is part of a small but vocal minority of neo-Maoists , said criticism of the Great Leader was a consequence of his unflinching support for the masses. On Friday, like-minded devotees will congregate in Shaoshan, a small town in central China where he was born in , to pay tribute to Mao. So the compromise position is to have some sort of low-key celebration here or there.

One-and-a-half million people died and much of the country's cultural heritage was destroyed. In September , with many cities on the verge of anarchy, Mao sent in the army to restore order. Mao appeared victorious, but his health was deteriorating. His later years saw attempts to build bridges with the United States, Japan and Europe. Search term:. Read more. This page is best viewed in an up-to-date web browser with style sheets CSS enabled. While you will be able to view the content of this page in your current browser, you will not be able to get the full visual experience.

Please consider upgrading your browser software or enabling style sheets CSS if you are able to do so. This page has been archived and is no longer updated.






















For the average user and the avid designer alike, buying a Mac may be the best bet, so long as the buyer can afford to pay a little extra. With a user-friendly operating system and multi-device ecosystem, buying an iMac , a MacBook , or a Mac Mini offers an easy-to-use, approachable take on the modern computer, and one that allows for seamless synchronization between other Apple phones and tablets.

Alternatively, if you like working with source code, are a PC gamer or are looking for the best budget computer option, a PC is the way to go. Those who tend to use cloud computing to the max and only exist on the internet should consider other options than Windows and Mac, like the Lenovo Chromebook Duet , which features Chrome OS.

In the Mac vs. Zachary Visconti is a writer for BestReviews. BestReviews is a product review company with a singular mission: to help simplify your purchasing decisions and save you time and money. BestReviews spends thousands of hours researching, analyzing and testing products to recommend the best picks for most consumers. BestReviews and its newspaper partners may earn a commission if you purchase a product through one of our links.

Skip to content. The differences between Macs and Windows PCs. Best Mac computers. Pros of buying a Mac. The most commonly cited positive of buying a Mac is its user-friendliness and approachability.

Even for those brand new to computers, Mac OS tends to be more intuitive than Windows. Mac's seamless integration between iPhones, iPads and its computers make it a no-brainer for anyone who already has a device in the Apple ecosystem.

For my documents, I did some research and decided to use Google Backup and Sync. I used it to back up my whole Documents folder from my old MBP into the cloud, then download all of it as one big zip file to my new PC. I extracted it into the local Documents folder on my new PC, then set Backups and Sync to back up that folder from my HP, which would ensure that everything I do in those folders from then on would be instantly backed up should my new computer decide to self-destruct.

My external hard drives were another pain point. Because I do a lot of photo and video work, I had quite a collection of large, full hard drives that were now effectively paperweights.

So, for each of the hard drives I wanted to continue using I had to buy a new, blank hard drive, then use a program on my MacBook Pro Carbon Copy Cloner to copy the old drives to news ones, which would be in the exFAT format readable by both operating systems. It took my MacBook Pro 44 hours to duplicate 1. Muscle memory is very stubborn, so this made things frustrating.

How does that happen? On the third day, I somehow managed to infect my browser with some adware. I think it piggy-backed in with a disk utility I downloaded. Those gripes are all software-related. On the hardware side, things were better. The laptop was fast and responsive, the screen was sharp, and the keyboard was easy to type on. Having a legacy USB port proved to be invaluable, especially in those early days as I was using a thumb drive to move files from the old machine to the new one.

I also loved having a built-in micro SD card reader, even if I would have preferred a full-sized SD card slot. But still, better than the dearth of connectivity options on the MacBook Pro.

Apple really set the standard in the modern capacitive touchscreen world when the original iPhone came out. Considering how good the touchscreen on the iPad and later iPad Pro got, I assumed a touch-display on a MacBook Pro was just around the corner. After spending about 18 months with the HP Spectre x, I can tell you unequivocally that having a touchscreen on a laptop is great. It just makes multitasking that much easier.

A touchscreen is also great for working with images in Adobe Lightroom and Photoshop. When I needed to do some shading or make a precise selection, it was far easier to do that with the HP Tilt Pen a powered stylus than it was with the trackpad or even a mouse.

No, the pen-on-screen system is not as accurate as a Wacom tablet, but for a minimal, travel-friendly setup, it works very well.

As a user, there are zero disadvantages to a touchscreen. Not only do most companies make and update their macOS software first hello, GoPro , but the Mac versions by and large work better than their Windows counterparts. Some programs you can't even get for Windows. Carbon Copy Cloner, one of the most important programs in my arsenal, just plain doesn't exist for Windows.

There are, and literally all of them suck quite thoroughly. Even when apps do exist for both platforms, the Windows versions are far buggier. Even basic things like two-finger scrolling through a timeline in Adobe Premiere are completely borked. I hear random chimes all the time. How do you do that, you ask? Why, just follow these elaborate steps through the baffling Registry Editor and enter some code into a sea of gobbledygook. By contrast, the same task in macOS involves four straightforward steps.

The one arena where Windows has the software advantage is gaming. When you calculate the cost of ownership in that way, Macs win easily. All you have to do is compare the value of a Windows PC from, say, three years ago which is often close to zero , and compare that to what you can get for your 3-year-old Mac. We tried shopping for a PC just to compare, and after about 15 minutes our eyes glazed over. Our friendly and expert staff is happy to help you through the entire process.

Those same people often get frustrated that if you want to run the Mac OS, your choices are essentially limited to Apple, and then the limited choices they give you within that. In general, when Apple makes assumptions with its software, it gets it right, Microsoft often gets it wrong. Most often, however, it just gets annoying. Most people spend more time undoing the presumptions than benefitting by them… Microsoft is just horrible at getting in the way. While this has changed just a little as Apple has gained ground on Microsoft, Mac users are still living in relative bliss with the lack of viruses, spyware and malware.

Apple is further assisting with backing up with the utilization of iCloud, something especially appreciated in this age of people using multiple devices, such as the iPhone and iPad.

Microsoft makes the software.






















In fact, exercise causes an immediate increase in blood pressure -- particularly in the systolic, or top blood pressure number. How much your blood pressure changes during exercise correlates with your fitness level and health status, as well as the type and intensity of exercise, and these changes may provide important clues to your health. Blood pressure measurements consist of two numbers. The first figure, the systolic, represents the pressure when your heart is contracting, and the second, or diastolic number, is a measure of the pressure in between beats -- when the heart is relaxed.

Blood pressure is greatly influenced by cardiac output, or how much blood your heart pumps per minute, and peripheral resistance, which is the resistance of arteries to blood flow.

These factors help to explain why blood pressure varies person to person, and why it changes with exercise. How much your blood pressure increases with exercise depends on your usual resting blood pressure levels, and your work rate, or the type, intensity and duration of physical activity.

During exercise, your heart rate -- and systolic pressure -- go up, because cardiac output increases to pump more blood and oxygen to working muscles. In people without hypertension, most types of exercise can push systolic blood pressure to the to mm Hg range, and intense exercise such as weight lifting can temporarily push systolic pressure to even higher levels.

Exercise also causes vasodilation, or the widening of blood vessels, which increases blood flow and decreases peripheral resistance -- which, in healthy people, keeps the diastolic blood pressure from rising during activity.

Hypertension, 35, There are two million new cases of hypertension each year, and it is estimated that two-thirds of American will have high blood pressure some time in old age Neiman This article will examine the impact of aerobic exercise and hypertension and review recent research on the affect of progressive resistance exercise on resting systolic and diastolic blood pressure in adults.

Hypertension the Health Problem High blood pressure kills more than 37, Americans each year and contributes to the deaths of , individuals Neiman When undetected and untreated, hypertension may lead to a number of abnormal problems. The heart sometimes begins to increase in size, which eventually can cause heart failure. The blood vessels in the kidneys often begin to narrow, which may lead to kidney failure.

Finally, hypertension will sometimes lead to a hardening of the arteries throughout the body, which can provoke a heart attack, stroke, or kidney failure. In population areas and societies where physical inactivity and obesity are present, and salt and alcohol intake are high, hypertension is common Neiman Aerobic exercise is a potent intervention in lowering and preventing the incidence of hypertension.

It is interesting to note that most of the lowering of systolic and diastolic blood pressure in those with hypertension occurs within a few weeks of consistent aerobic training.

The exact mechanism how aerobic exercise helps to lower high blood pressure is unclear, however it is theorized that biochemical, neural and hormonal changes in the blood vessel walls induce an acute and long-term blood vessel relaxation. The research has been unclear as to the relationship of progressive resistance exercise and those individuals with hypertension.

Studies in this area have been criticized for having small sample populations and inadequate research designs. However, Kelley and Kelley recently employed a powerful quantitative research technique known as meta-analysis, to better ascertain what is truly known about the use of resistance exercise as a nonpharmacological intervention in lowering resting blood pressure in adults.

The length of training in all the studies was from 6 to 30 weeks, with a mean training period of 14 weeks. During rest and peak exercise, a significant shortening of the relative duration of LV diastole Baseline and peak exercise LDT RR values were inversely related to cardiac output reserve and exercise duration. In multivariate analysis, LDT RR at peak exercise was identified as an independent predictor of cardiac output reserve. The disproportionate shortening of diastolic time may significantly impair cardiac efficiency by restricting diastolic filling.

This is a preview of subscription content, access via your institution. Rent this article via DeepDyve. Bonow RO. Left ventricular diastolic function in hypertrophic cardiomyopathy. Herz ; Hypertrophic cardiomyopathy: The search for obstruction. Circulation ; Article PubMed Google Scholar. Systole-diastole mismatch in hypertrophic cardiomyopathy is caused by stress induced left ventricular outflow tract obstruction.

Am Heart J ; J Am Coll Cardiol ; Article Google Scholar. Recommendations regarding quantitation in M-mode echocardiography: Results of a survey of echocardiographic measurements. Doppler echocardiographic assessment of the pressure gradient during bicycle ergometry in hypertrophic cardiomyopathy.

Am J Cardiol ; Loss of diastolic time as a mechanism of exercise-induced diastolic dysfunction in dilated cardiomyopathy.

Fully automated equilibrium radionuclide ventriculography. Proposal of a method for routine use: Exercise and follow-up. Eur J Nucl Med ; Mantysaari M, Lansimies E.

Eur Heart J ; Causal relation between the pressure gradient and left ventricular ejection time in hypertrophic cardiomyopathy. Left ventricular outflow tract obstruction in patients with hypertrophic cardiomyopathy: Increase in gradient after exercise.

Hypertrophic cardiomyopathy is predominantly a disease of left ventricular outflow tract obstruction. Limitations of the New York Heart Association functional classification system and self-reported walking distances in chronic heart failure. Heart ; Exercise intolerance in patients with chronic heart failure: Role of nutritive flow to skeletal muscle.

Determinants of exercise capacity in hypertrophic cardiomyopathy.






















The ship had advanced safety features, but there were not enough lifeboats to accommodate all of those aboard. Only 1, people can be carried in lifeboats. Four days into the crossing and about miles km south of Newfoundland, she hit an iceberg at pm ship's time. The glancing collision caused Titanic's hull plates to buckle inwards along her starboard side and opened five of her sixteen watertight compartments to the sea; the ship gradually filled with water. Meanwhile, passengers and some crew members were evacuated in lifeboats, many of which were launched only partly loaded.

By AM, the giant ship broke apart and foundered, with over people still aboard. Just under two hours after the sinking, the Cunard liner RMS Carpathia arrived and brought aboard about survivors. The famous British ship that was designed to be unsinkable, but it finally sank on 15 April after colliding with an iceberg during its long trip from Southampton, UK to New York City, US.

About 1, people died, and the largest ship made at the time led to one of the biggest disasters in modern history. Rose Had the Life Everyone Dreams Of In the beginning of the Titanic movie, we see Rose as an old woman living what appears to be a simple yet good life. Titanic Has a Wide Emotional Range When people watch a movie, it is important that they are touched by it.

The Story of the Titanic Is Pretty Accurate Some people love history, and some find it boring, so for those that do nto want to do any research on what happened to the RMS Titanic , the movie tells it pretty accurately.

Even those who sneer at its sappy central romance and occasionally ham-fisted acting hello Billy Zane , have to admit that Titanic looks suitably spectacular from start to finish. While Leo brought the youthful charm, Winslet brought the class with a star-making performance which, unlike her co-star, was recognised with an Oscar nomination.

Then only 20 years old, Winslet imbues what is essentially a poor little rich girl character with a steely determination and genuine heart which ensured audiences cared about and believed in both her romance and her overall fate. The old couple in bed waiting to die, the mother comforting her kids as the ship goes down, the violinists deciding to play on for one last song. Inspired by the Celtic New Age of Enya — who was initially approached to compose the soundtrack by James Cameron — the late composer produced a powerful and emotive score which perfectly complemented its surrounding tragic drama.

It is love that exceeds the deserts of the beloved. What I can tell you, risking puns, is that it swept me off my feet almost from the get-go, a grand epic romance-disaster that reminded me, in the middle of my overstuffed-with-movies life, of what we mean when we talk about the power of cinema. It has room enough for a slightly campy hand-to-window moment in a steamed-up car, a comedic routine involving a fire axe and a pair of handcuffs, and a touchingly authentic scene of sacrifice on a bit of floating wreckage in the icy Atlantic.

But to me, these are minor matters. The film is either a masterpiece, or something very close. Titanic is two movies stitched together: a swoony teenage fantasy for the ages, and a massive disaster movie that rivals any disaster movie to come out of Hollywood either before or since.

The lengthy runtime makes perfect sense by this rubric, and you can see the seam where the movie pivots from one to the other, almost exactly at the halfway mark. I fell hard for the romance. It fulfills the human desire, as Ebert put it, to be cherished, the experience of having someone look at you as if you fill their whole field of vision and spill over the edges. Those are good things to want and better things to experience, but as we age, time usually moderates these sorts of desires.

Watching Titanic , they all come roaring back. Titanic leans hard into its dreams and, for my money, succeeds. I watched it for the first time at age 34, but I felt 14 again. Nestled into my theater seat, clutching a forgotten bag of Skittles, the pieces at last fell into place. I finally understood why my peers were so dedicated to Leonardo DiCaprio.

I also understood why Titanic launched Winslet into stardom. In an over-the-top role, she was equal parts heroine, rebel, and action star all at once, and her laugh was infectious. Finally, I understood why so many people went back again and again to see the movie. Titanic came out just as the Internet was starting to rise up and merge into the ocean of our lives, and though, at that point, most of the hate directed at the movie was conversational and anecdotal, in spirit it was computer-viral.

It was about fragments of resentment banding together and organizing themselves into a cult, a movement, an anti-fan club. What gave the movement its motivating force? What made the fragments band together like angry iron filings? It was a movie that found love in the machine, even as the machine was destroyed. No wonder the haters hated it. Their real identification was with the machine.

Home Article 'Titanic' is a great film.






















Here are all the reasons your body will thank you for adding the ruby-hued fruit to your plate. Strawberries are rich in fiber and vitamin C, a nutrient pairing that's great for reducing oxidative stress, which can reduce heart disease and cancer risk. Plus, strawberries are a good source of potassium , which has been shown to help protect against heart disease.

Eating strawberries may also reduce your chances of having a heart attack. A study from Harvard of nearly , young and middle-aged women found that eating at least three servings a week of strawberries reduced the risk of heart attack by 32 percent. Researchers attributed the effect to high levels of antioxidants called anthocyanins in strawberries.

Another small study in the Journal of Nutrition found that people who ate 50 grams about three cups of freeze-dried strawberries a day had lower levels of "bad" LDL cholesterol in their blood after 12 weeks. Alexandra Caspero , RD, a registered dietitian based in St.

Louis, MO, notes, that other studies have found that berries can help reduce platelet aggregation when platelets stick together , another risk factor for heart disease. Regularly eating berries, including strawberries, has been linked to reduced risk of cancers, including esophageal cancer and lung cancer , in animal studies; the research is promising but still mixed in human studies.

Strawberries contain protective plant compounds called polyphenols, two of which — ellagic acid and ellagitannins — have shown promise in helping to manage some of the effects of type 2 diabetes.

In particular, they appear to regulate blood sugar and manage blood pressure. More research is needed to validate these effects in humans. Studies suggest that strawberries may prevent certain cancers. The protective effect is thought to be thanks to a combination of polyphenols including ellagic acid and ellagitannins, which appear to halt the growth of cancer cells in animal studies.

More human studies are needed to establish the correct method of action and to confirm the effects. Strawberries have a low glycaemic index GI and as such help moderate blood sugar release. Studies suggest that a diet with plenty of low GI foods may be beneficial for weight management and for reducing the incidence of obesity-related diseases.

Strawberries are also low in calories, yet sweet tasting so may be helpful as a sweet fix. Although most of us can enjoy strawberries without a problem, they are a common allergen , especially for young children. If you have allergies to birch pollen or apples, you are more likely to develop a secondary food allergy to strawberries. If this is relevant, you should avoid strawberries. Strawberries, along with fruits including apples, peaches, avocados and blueberries contain natural chemicals called salicylates.

Some people are sensitive to these compounds and may experience an allergic reaction including skin rash and swelling. At the start of the study, the women reported how often they ate strawberries. Fourteen years later, over 2, of the women had diabetes. Compared to women who rarely or never ate strawberries, those who ate strawberries at least monthly had a lower risk for diabetes. Further, the American Diabetes Association identifies berries, including strawberries, as one of the top 10 superfoods for a diabetes meal plan.

Reason 3: Strawberries are good for your heart Anthocyanins are phytonutrients or natural plant chemicals found in strawberries. A study published in Circulation found that high anthocyanin intake more than 3 weekly servings of strawberries is associated with a lower risk of heart attacks in middle-aged women.

As it turns out, a healthy daily dose of berries, including strawberries, in your diet can play a big role in staving off dementia in old age. It takes a little more work, but here are long-stemmed strawberries. Reason 5: Strawberries have less sugar than many realize Folks believe that strawberries have more sugar than other fruits. However, strawberries actually contain the lowest amount of sugar 7 grams per one-cup serving compared to the top 5 popular fruit oranges, bananas, grapes, apples, and strawberries.

Gorgeous handful of fresh picked strawberries. However, when asked which they consume the most, only 12 percent of respondents indicated strawberries as their most consumed fruit. For this reason, people who consume insufficient amounts of vitamin C can develop gum problems. Strawberries, which are a good source of vitamin C, help maintain a healthy mouth.

Strawberries have been proven to help protect against cancer thanks to the anthocyanins they contains. Fresh ripe organic red strawberries are harvested in a garden. Shutterstock Photo. It was never a secret that consuming strawberries is beneficial for health. It is summertime, which means we can have more fresh fruits and berries to pick from. So, what are the good aspects? Here are 12 benefits of strawberries that you might not know.

Supports the immune system Vitamin C is one of the most important vitamins that support the immune system. Effective against anemia Strawberries are a fruit rich in folate, that is, vitamin B Improves skin quality The skin normally has a high concentration of vitamin C.






















He died at his beloved Spiegel Grove in Several family portraits and original furnishings adorn the house. The library in particular contains numerous mementoes including two framed photographs of Lincoln.

Hayes, an avid reader, designed the room to display portraits of former political greats. The graves of Lucy and Rutherford Hayes are on a small hill at the south end of the estate.

The State of Ohio constructed a museum and library building on the grounds of Spiegel Grove in Two additions date from and The research library has approximately 70, volumes, including the president's personal library. The exhibits in the museum focus on the life and times of Rutherford B. Hayes, his family, and Ohio history.

A life-size diorama of Hayes in camp during the Civil War illustrates his active participation in that conflict. The Rutherford B. For mapping purposes only the address is Spiegel Grove.

Click here for the National Historic Landmark registration file: text and photos. Hayes home is also an Ohio Historical Society Site. Daily tours of both are available year-round, Tuesday —Saturday am to pm and Sundays and Holidays pm to pm. Visitors can opt to tour one building or both.

Tours of the Hayes Home are guide led and take 45 minutes. The Hayes Museum is a self-guided tour, with docent-led tours available for groups of 15 or more by prior arrangement. For more information visit, the Rutherford B. Hayes Presidential Center website or call toll free The website provides a wealth of information on the place and people of Spiegel Grove.

Spiegel Grove Rutherford B. Hayes Presidential Center Ohio. Historians have blamed Hayes for the end of Reconstruction, for breaking the Great Strike of , for championing the gold standard, for a Native American policy that aimed at acculturation, for negotiating a treaty that led to Chinese exclusion, and for being an inconsistent civil service reformer. Yet, it remains hazardous to dismiss Hayes so summarily. Too often scholars have measured him against the ideals of a later era.

Historians have not adequately understood his limited options, nor have they always interpreted his actions fully, or even fairly. He did not break the Great Strike, for example, and only sent troops to stop riots when state and local authorities legally requested. Additionally, for all practical purposes, Reconstruction was over when Hayes took office. His only real choice was not whether but when troops had to cease protecting Republican governments in South Carolina and Louisiana.

His opposition to inflation and support of the gold standard—policies supposedly against the interest of workers and farmers—were accompanied by the return of a general prosperity. His Indian policy was indeed paternalistic and did aim at acculturation, but he stopped the removal of some Native Americans to the Indian Territory. At the same time, he embraced a policy of peace, which had its beginnings under Ulysses S. Grant, and not one of annihilation.

The treaty with China accommodated the racist temper of Californians and of Congress, but its aim was restriction, not exclusion. Reformers were not entirely happy, and spoilsmen were angered by Hayes's civil service policy, but he left the party machinery sufficiently intact to win in In addition, the experiment with the New York customhouse proved the feasibility of reform and made possible the passage of the Pendleton Civil Service Reform Act.

Hayes is also significant for the strikingly modern actions he took to enhance the power of the presidency. He defeated Republican senators over the so-called "courtesy of the Senate" convention and did not let them dictate appointments in the field service.

He also defeated the Democratic congressional majority's stance toward the President's legislative role by not letting it destroy his veto power. In defeating the Democrats in the "Battle of the Riders," he relied on the power of public opinion, which he aroused in his stirring veto messages. Hayes traveled more widely than any previous President and, although he did not electioneer, he used every opportunity to speak on issues close to his heart.

In this manner, he bypassed Congress to appeal directly to the people. After winning the presidency in one of the most contested elections in American history, he led the country through the end of Reconstruction and resigned after one term in office. Hayes was born on October 4, , in Delaware, Ohio. Three years later he emerged with a law degree from Harvard Law School and began practicing law in Lower Sandusky, Ohio.

Four years later, in , Hayes picked up and moved to the more bustling Cincinnati, where his law practice flourished and where he was first drawn to the Republican Party. Hayes fought in the Army during the Civil War, rising to the rank of major general and sustaining severe injuries at the Battle of South Mountain.

While Hayes was still in the Army, Republicans from Cincinnati convinced him to run for the House of Representatives, and he was easily elected, entering Congress in December Two years later, he had resigned and begun his first term as governor of Ohio, going on to serve three terms. Despite such widely known figures as Mark Twain campaigning on his behalf, Hayes never thought he could win, and when the popular vote came in, Hayes had lost by a narrow ,vote margin.

However, contested electoral-college votes in Florida, Louisiana and South Carolina kept the candidate afloat: If all of the disputed votes went to Hayes, he would win; if even a single vote went to Tilden, Hayes was finished. In what would end up being one of the most controversial elections in American history, uncertainty reigned for months after the election, until January , when Congress established an ad hoc electoral commission to decide the dispute once and for all.

The commission was composed of eight Republicans and seven Democrats, so it was no surprise that it decided in favor of Hayes by an vote, handing the final electoral tally to Hayes by a count. The result was contentious, and to avoid fueling any burning flames of resentment, Hayes secretly took the oath of office on Saturday, March 3, , in the Red Room of the White House.

The Democrats allegedly agreed to the decision in exchange for the withdrawal of federal troops from South Carolina and Louisiana, marking the end of Reconstruction in the South, in what is called the Compromise of Hayes did remove the last federal troops from the South, which has hurt his reputation with some historians. But others said Hayes had no choice, and most federal troops had already left the South during the Grant administration.

Arthur would become President in Under Hayes, the American economy also recovered from the disastrous Panic of Today, Hayes is little remembered in the United States, but he is treated as a national hero in one nation: Paraguay.






















Despite its political prominence as the county seat, Fairfield was more isolated in its early years, when it had neither a port nor other easy access to larger market towns.

Well into the 20th overshadowed by its neighbor and rival, Suisun City. However, Fairfield had much more to offer than just its government center. Following its incorporation as a city in , a bond measure was passed that created much- needed improvements, and with the re-routing of the Lincoln Highway through the town in , Texas Street finally developed into a bustling center.

Over the years, many other businesses began to come to Fairfield, attracting residents from the century, Fairfield did not have many residents and was often surrounding valleys and vicinities. Today, Fairfield is shaped by the rapid growth along the Interstate 80 corridor and the influence of nearby Travis Air Force Base, which was built east of town in and provides a tremendous boost to the local economy.

Fairfield is the home to a diverse industrial and commercial sector, employing workers in a variety of professional fields. The History of Fairfield and Solano County. The county bears the Spanish name for Saint Matthew. As a place name, St. Matthew appears as early as , and the arroyo, the point and the settlement at the unofficial San Mateo Mission are all so designated on the early maps.

Until about , the name appeared as San Matheo. The Santa Barbara Channel received its name from Sebastian Vizcaino when he sailed over the channel waters in In , Padre Junipero Serra dedicated a site near the channel for a presidio and on Dec. The county derives its name from the mission. In the original act, the county was given the name of Branciforte after the Spanish pueblo founded there in Less than two months later, the name was changed to Santa Cruz.

Established in and completed in , the Santa Cruz Mission was destroyed by earthquake in , but a smaller-scale replica was erected in This county was named after Mount Shasta. The name of the tribe was spelled in various ways until the present version was used when the county was established.

Created and named after the mountain range. The origin of the word siskiyou is not known. Still others attribute the name to a local tribe of Native Americans. The county derives its name indirectly from that of the Franciscan missionary, Father Francisco Solano, whose name was given in baptism to the chief of one of the Native American tribes of the region. The word Stanislaus is a corruption of Estanislao, the baptismal name of a mission-educated renegade chief who led a band of Native Americans in a series of battles against Mexican troops.

He was finally defeated by General Mariano G. Vallejo in The county is named for the Stanislaus River, first discovered by Gabriel Moraga in , and later renamed Rio Estanislao for the chief.

Sutter County was named after General John Augustus Sutter, a native of Switzerland, who obtained a large land grant from the Mexican government and called his first settlement New Helvetia now the City of Sacramento. In , the general established a great stock ranch in this area to which he retired in when gold seekers deprived him of most of his holdings at Sacramento. The county is named for the City of Tehama. Reading, who was under the mistaken impression that the stream emptied into Trinidad Bay.

Trinity is the English version of Trinidad. While hunting for deserters in , Commandante Fages discovered a great lake surrounded by marshes and filled with rushes which he named Los Tules the tules.

It is from this lake that the county derives its name. The root of the name Tulare is found in the Mexican word tullin, designating cattail or similar reeds.

Vallejo stated that the river was named Uba by an exploring expedition in because of the quantities of wild grapes uvas silvestres in Spanish which they found growing on its banks. Skip to Navigation Skip to Content.

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Mario made his debut in the video game hit Donkey Kong. As a result, everything, including Mario, had to be created within rather narrow design constraints.

In , he sat down with CNN to explain the method behind the mustache:. We had to draw Mario as a small character and at the same time, we had to make him look human. To do that, we needed to draw a distinctive feature for him, such as giving him a big nose.

It is difficult to show facial expressions with small characters. In real life, people can have different colored head hair and facial hair. It's not too uncommon. Also, Mario's mustache happens to be a really dark brown. I also mistook it for black myself, but on closer look, it's brown. User Info: HylianAngel. Sign Up for free or Log In if you already have an account to be able to ask and answer questions. Question Status Floating Mario?

Answered How do i get Wiggler to let Luigi and Mario pass? Answered Where is the best place to grind as Mario and Luigi? Answered How does Mario and Luigi tunnel underground?? Answered What Mario game is this story based off of? Ask A Question. Keep me logged in on this device. Forgot your username or password? Floating Mario? How do i get Wiggler to let Luigi and Mario pass? Bowser's only child is Bowser Jr. Do you consider it part of the classic canon of Mario platformers or is it a spin-off in your mind since the player controls Yoshi?

After that, the Yoshi series continued on its own. As developers, do we consider it to be part of the core Mario series? The answer is yes. In Super Mario World, the enemy Chargin' Chuck dresses like a football player but often throws baseballs.

Why does he do that? Takashi Tezuka: Well, at the time, one of the things we were trying to do with the resources we had was to introduce some variation. So we made the decision that this might be kind of weird, but let's go ahead and have some of these guys throw baseballs. Miyamoto: I think that maybe the ones that threw baseballs were a little bit more fun, so we used a lot of them.

Mario's mustache and eyebrows are black, but his hair is brown. Does he dye his hair, is that natural, or is that a toupee? SM: This goes into [a] technical explanation of the number of colors that you could use in the early days. Mario was originally red, blue, white, and black. Maybe it was around the time of Super Mario Bros. What really happened was that, when drawing the character, it became much easier to draw the mustache as an extension of the outline of his nose. Using that same color of black, we drew the mustache.

But then we felt bad for Mario that he didn't have a distinct hair color, so we gave him brown hair.

Mario has been a boxing referee, a doctor, an Olympian, and a carpenter. Are all these official careers in Mario lore? If he has a medical degree, why does he continue his plumbing business? SM: There's really only one rule in terms of the things that Mario does.






















Even though your menstrual cramps may be normal, it doesn't mean there's nothing you can do to relieve the pain. Here are a few things you can do besides eating chocolate. Do you need relief from your period cramps right away? Lying down with a heating pad is one of the best ways to relieve menstrual cramps.

In fact, keeping heat applied to the area of your belly where the pain is the worst can be just as effective as using a pain killer like ibuprofen. But since you can't stay connected to a heating pad all day, try taking a warm bath, using a hot water bottle, or applying a heat patch instead. The key is to keep the heat as continuous as possible. Many of the same over-the-counter pain relievers you use for headaches can also help relieve menstrual cramping pain.

You should start taking a pain reliever when you begin feeling symptoms of period cramps and continue taking the medicine for two or three days, or until your symptoms are gone. Need a reason to work out during your period?

The endorphins produced while exercising or having sex can help relieve your menstrual cramps. Any type of exercise, whether it be aerobic or simply stretching has been found to lessen the pain of your cramping. When you have period cramps you just can't seem to relieve with the methods mentioned above, your doctor may prescribe birth control, which provides your body with hormones that may reduce your menstrual cramping. Talk to your doctor about your birth control options.

They even claim it can help with period pain. One thing is for certain though is that they can be pretty dangerous.

One case study in Canada found that a woman had severely burnt herself after using vagina steaming to help her manage her painful prolapsed vagina.

It could also burn the delicate skin around the vagina the vulva. Many endometriosis experts believe that continual use of a hot water bottle may even worsen symptoms. We understand that endometriosis flare-ups are caused by muscular contractions as the body tries to excrete the endometrium.

When heat is applied to the affected area, the fascia begins to loosen, as previously mentioned and then as it cools it hardens.

According to one study , this can lead to worse endometriosis pain because it reduces the flexibility of the fascia and forms a rigid layer of tissue. Because heat hardens the fascia, you then need higher temperatures to help the fascia and surrounding muscles relax which then hardens the fascia even more. There are many risks associated with using hot water bottles and heat of any kind for pain relief. Scars, burns as well as permanent muscular damage only scratch the surface of the harm that heat therapy does to women who suffer from severe period pain.

Not only is it an impractical, and often ineffective form of treatment, but it can even worsen symptoms that women already find debilitating. We should be able to use products without the fear of hurting ourselves, particularly during menstrual cycles.

We believe more natural, kinder alternatives are out there and we want to be here to help support those women on their pain relief journey. Time for the shameless plug - this is why we created our groundbreaking Monthly Patches , not heat, not cooling, just an all-natural tingling effect which goes further than a hot water bottle without any of the downsides!

Give it a go for yourself! She loves talking about period positivity and body positivity and, let's face it, loves a good debate. Shop All translation missing: en. Store Finder. How does heat therapy affect period pain? What is the rebound phenomenon? What happens if you use a hot water bottle for period pain? What about yoni steaming? Is vagina steaming safe?

Can I use heat for my chronic pain? Why shouldn't I use my hot water bottle for period pain? These results appear promising but should be interpreted cautiously because they are based on relatively few trials with an unclear risk of selection bias.

We included only RCTs to remove potential bias and did not have any language restrictions. Although our literature searches included English and Korean databases, and also included searching by hand for relevant articles, we cannot be absolutely certain that all relevant RCTs were found. The meta-analysis included small numbers of studies with relatively small sample sizes. This contributed to imprecision in estimates. There were variations in the duration, type of heat therapy e.

A recently published review, which examined the same topic as this article 11 , included a non-RCT that was excluded from our review. Additionally, it failed to include several important studies 16 , 17 , 19 that were included and analyzed in our review. NSAIDs appear to be an effective treatment for dysmenorrhea, although women using them need to be aware of the substantial risk for AEs Hormone contraceptives are available only for patients who do not plan to become pregnant 9.

Our systematic review showed the clear benefit of heat therapy for menstrual pain in women with primary dysmenorrhea. Whether this translates into long-term clinical benefits has yet to be demonstrated. One argument for using heat therapy for the management of dysmenorrhea may be that it causes fewer AEs than conventional drugs.

However, there was no evidence that there is a difference among them with regard to AEs. If heat therapy were effective and safe for the management of dysmenorrhea in both the short- and long-term, it could become a first-line non-pharmacologic treatment to decrease menstrual pain in women with primary dysmenorrhea, particularly those with contraindications for NSAIDs. This systematic review and meta-analysis suggests that heat therapy was associated with a decrease in menstrual pain in women with primary dysmenorrhea.

These results are consistent with the recommendation of local heat as a complementary treatment for dysmenorrhea 9. We need to compare the effects of various heating modalities with those of other general interventions in terms of short- and long-term outcomes as well as cost-effectiveness. A well-designed multicenter trial to address this issue and provide robust evidence of benefit is warranted to clarify the role of heat therapy in this population.

Each search term was composed of a disease term e. No language restrictions were imposed. The search strategies are presented in online Supplement 1. Similar search strategies were applied to the other databases. Observational, cohort, case—control, and case series studies were excluded as were qualitative, uncontrolled trials, and laboratory studies.

Patients of any age with primary dysmenorrhea were included in the systematic review. Dysmenorrhea secondary to other pathologies, such as uterine myoma, endometriosis, or infection, was excluded in this review. Randomized studies of superficial or deep heat therapy, either as the sole treatment or as an adjunct to other treatments applied in both groups intervention and control groups in the same manner, were included.

We included any type of control intervention, including no treatment, placebo, and conventional medication. RCTs that compared different heat treatments were excluded. The primary outcomes were reduction of menstrual pain only during the intervention or as a result of the intervention measured using a visual analogue scale VAS or numeric rating scale NRS.

The secondary outcomes were scores on validated pain questionnaires, QoL, and AEs. Two authors JJ and SHL performed the data extraction and quality assessment using a predefined data extraction form. The form included information pertaining to the first author, study design, language of publication, country where the trial was conducted, clinical setting, diagnostic criteria, number of participants allocated to each group, drop-out number, treatment duration, outcome, outcome results, and AEs associated with heat therapy.

When studies reported outcomes at more than one time point, a similar measurement point in other studies was used for the analysis, such as at the end of treatment or the first menstrual cycle after treatment. Any disagreement among the authors was resolved by discussion among all authors. When the data were insufficient or ambiguous, JJ contacted the corresponding author by electronic mail or telephone to request additional information or clarification.

The risk of bias was assessed using the risk-of-bias assessment tool from the Cochrane Handbook ver. Disagreements were resolved by discussion among the authors. Statistical analyses were performed with the program Review Manager ver.

Data were pooled and expressed as the mean difference MD or standardized mean difference SMD for continuous outcomes using random-effects models, because high levels of heterogeneity had been anticipated.

When substantial heterogeneity was detected, we explored the sources of heterogeneity by performing a subgroup analysis according to the type of intervention or control group. If some factors e. We assessed publication bias by using a funnel plot if 10 or more studies were included. We made our best efforts to analyze data on an intention-to-treat basis, and attempts were made to obtain missing data from the original investigators.

When these attempts were unsuccessful, we did not substitute data for missing data but analyzed only the available data. Supplementary information accompanies this paper at National Center for Biotechnology Information , U. Sci Rep. Published online Nov 2. Junyoung Jo 1, 2 and Sun Haeng Lee 3. Author information Article notes Copyright and License information Disclaimer.

Sun Haeng Lee, Email: moc. Corresponding author. Received Apr 5; Accepted Oct This article has been cited by other articles in PMC. Supplementary information. Abstract Primary dysmenorrhea, which is menstrual pain without pelvic pathology, is the most common gynecologic condition in women. Introduction Primary dysmenorrhea refers to painful menstrual cramps in the lower abdominal region during menstruation in the absence of any discernible macroscopic pelvic pathology 1.

Results Description of included trials After removing duplicates, studies were screened and 15 full-text articles were assessed for eligibility. Open in a separate window. Figure 1. Table 1 Baseline characteristics of included studies. Pain relief score on 6-point scale B. Reduction in pain intensity during days 1—2 on NRS A. Pain relief score during day 1 on 6-point scale B.

Abdominal muscle tightness and cramping during day 1 on NRS A. Maximum VAS score B. Participants taking pain medications A. Sensual pain score on point scale B. Emotional pain score on point scale C. Current pain score on point VAS D.

Total pain score on 6-point VAS A. Mid-treatment pain intensity on cm VAS T3. End of treatment pain intensity on cm VAS T2. Table 2 Details of the heat therapies used in the RCTs. First author Year Method Treatment region Treatment duration Akin Wearing a kidney bean-shaped ultra-thin medical device that supplied heat at a constant temperature of






















The additional strategies below are other things that you may try if you and your doctor determine that they could be appropriate. Exercise more often. Both aerobic and strength exercise may help significantly decrease globulin levels in people [ 14 ]. In both men and women, more days per week of either aerobic or strength exercise were significantly associated with lower globulin [ 14 ].

You may also need to stop taking protein supplements, as these may be causing higher protein and globulin levels [ 15 ]. Drink more water to prevent dehydration [ 2 , 16 ].

Zinc may help prevent dehydration due to diarrhea, according to limited studies [ 17 ]. Electrolytes can also help with dehydration due to diarrhea [ 18 ]. Limit alcohol intake; alcohol can worsen dehydration [ 19 ]. Try to reduce stress, since acute stress may increase certain types of globulins [ 20 ]. The conditions we discuss here are commonly associated with low globulin, but this single symptom is not enough for a diagnosis. Work with your doctor to discover what underlying condition might be causing low globulin levels and to develop an appropriate plan to improve your health.

The most important thing is to work with your doctor to treat any underlying conditions causing your low globulin levels. Eating a diet with enough nutrients will prevent malnutrition and prevent your protein levels from becoming too low. Eating lean protein, such as fish and turkey, can help improve your total protein levels [ 2 ]. Also, it may be helpful to increase the consumption of foods that help with liver and kidney detoxification.

This should be comprised approximately of 3. Globulin Levels Tests will be used to determine the specific levels of different types of globulin in the blood stream. Low Globulin Levels. If the globulin levels fall below this normal range it can be a sign of several serious health conditions. Renal disease, hepatic dysfunction, celiac disease, inflammatory bowel disease IBD and acute hemolytic anemia can cause the globulin levels to drop.

Serum protein electrophoresis. This blood test measures gamma globulins and other proteins in your blood. It can be used to diagnose a variety of conditions, including disorders of the immune system and a type of cancer called multiple myeloma.

Other names for globulin tests: Serum globulin electrophoresis, total protein. What is it used for? Globulin tests can be used to help diagnose a variety of conditions, including: Liver damage or disease Kidney disease Nutritional problems Autoimmune disorders Certain types of cancer. Why do I need a globulin test? These tests, called liver function tests, may be ordered if you are at risk for liver disease or have symptoms of liver disease, which may include: Jaundice , a condition that causes your skin and eyes to turn yellow Nausea and vomiting Itching Recurring fatigue Fluid buildup in the abdomen, feet, and legs Loss of appetite A serum protein electrophoresis test measures gamma globulins and other proteins.

This test may be ordered to diagnose disorders related to the immune system , including: Allergies Autoimmune diseases such as lupus and rheumatoid arthritis Multiple myeloma, a type of cancer. What happens during a globulin test? Will I need to do anything to prepare for the test? Are there any risks to the test?

What do the results mean? Atlanta: American Cancer Society Inc. What is multiple myeloma? Being on bed rest for a long time can lower your protein level. If you are dehydrated your protein level may appear higher than it is. Dehydration may also lead to higher albumin levels. Making sure you have had enough water before the test will give an accurate result. If the band tourniquet is placed around your arm for too long during blood collection, this can also make your albumin level seem high.

Tell your healthcare provider about any symptoms you're having. Be sure your healthcare provider knows about all medicines, herbs, vitamins, and supplements you are taking. This includes medicines that don't need a prescription and any illegal drugs you may use. Search Encyclopedia. Why do I need this test? Symptoms of cirrhosis include: Fluid buildup in the belly, which causes pain and swelling Fluid buildup in the feet, ankles, or legs Fatigue Itching Nausea and vomiting Lack of appetite Weight loss Spiderlike blood vessels on the skin Yellowing of the skin and eyes jaundice This test can also help healthcare providers diagnose nephrotic syndrome, a condition that affects your kidneys.